This article describes the principal fashions for embedding research and the profitable experiences and challenges confronted in joint work by researchers and decisionmakers who participated in the Embedding Research for the Sustainable Development Goals (ER-SDG) initiative, and the expertise of the Technical Support Center. In June 2018, funding was granted to 13 pre-selected research initiatives from 11 middle- and low-income international locations in Latin America and the Caribbean (Argentina, Bolivia, Brazil, Colombia, Dominican Republic, Ecuador, Guatemala, Guyana, Haiti, Paraguay, and Peru).
The initiatives targeted on the system-, policy-, or program-level adjustments required to enhance health and construct on the joint work of researchers and decisionmakers, with a view to bringing collectively proof manufacturing and decision-making in health methods and services. The Technical Support Center supported and guided the manufacturing of high quality outcomes helpful for decision-making. This expertise confirmed the worth of initiatives similar to ER-SDG in consolidating bridges between research on the implementation of health insurance policies, applications, and methods, and the officers accountable for working health-related applications, services, and interventions.
Children 8-17 years of age and their caregivers accomplished PROMIS measures (bodily operate, melancholy, peer relationships, ache interference, and anger) between 6 months and 15 years after harm. Self- and proxy-report scores had been in contrast utilizing Wilcoxon signal rank check, Cohen’s impact dimension, and intraclass correlation coefficients (ICC) and by settlement throughout severity of signs primarily based on really helpful cutoffs. Ordinary least squares regression analyses examined child- (self-report rating, age, gender, and ethnicity) and proxy-related (relationship to baby) elements related to rating variations.
Two hundred and seventy 4 child-caregiver pairs accomplished the PROMIS measures. Mean baby age was 13.0 (SD:3) years. Caregivers reported considerably worse scores than the baby on bodily operate, ache, and anger (all p ≤ 0.01). The impact sizes had been small throughout all domains besides bodily operate. Similarly, ICCs had been all of average settlement. The proportion of dyads in settlement by severity teams was excessive with solely 5%-9% of pairs discordant. Only increased self-report rating was related (all p < 0.05) with better variations throughout all domains in regression analyses.
Research Synthesis, HIV Prevention Response, and Public Health: CDC’s HIV/AIDS Prevention Research Synthesis Project
Research synthesis, by qualitative or quantitative systematic opinions, permits for integrating outcomes of major research to enhance public health. We examined greater than 2 many years of work in HIV prevention by the Centers for Disease Control and Prevention’s (CDC’s) HIV/AIDS Prevention Research Synthesis (PRS) Project. We describe the context and contributions of research synthesis, together with systematic opinions and meta-analyses, by the expertise of the PRS Project.
We reviewed PRS Project publications and merchandise and summarized PRS contributions from 1996 to July 2020 in four areas: synthesis of interventions and epidemiologic research, synthesis strategies, prevention applications, and prevention coverage. PRS Project publications summarized threat behaviors and results of prevention interventions (eg, altering one’s notion of threat, educating condom negotiation abilities) throughout populations in danger for HIV an infection and intervention approaches (eg, one-on-one or group conferences) as the HIV/AIDS epidemic and science developed.
We used the PRS Project cumulative database and intervention efficacy opinions to contribute to prevention applications and insurance policies by identification of evidence-based interventions and growth of program steerage. Subject matter consultants and scientific proof knowledgeable PRS Project merchandise and contributions, which had been carried out by strategic programmatic partnerships. The impact of the PRS Project was seemingly facilitated by alternatives to immediately affect program and coverage as a result of of connections with different research translation actions and program and coverage choice making inside CDC.
Implementation and analysis of an e-health innovation for customized take care of sufferers with amyotrophic lateral sclerosis (ALS): protocol for a participatory motion research examine
In the absence of a treatment for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative illness, remedy consists of symptomatic administration by a multidisciplinary healthcare group and is especially geared toward optimizing sufferers’ high quality of life. Because the course of the illness is usually erratic and varies between sufferers, it’s crucial for sufferers with ALS to be carefully monitored. E-health improvements that may monitor illness development remotely have nice potential to tailor the care to the wants of particular person sufferers with ALS.
Therefore, the e-health innovation “ALS Home-monitoring and Coaching” was developed using a user-centered design course of and carried out at the University Medical Center Utrecht, the Netherlands in 2017. Because ALS Home-monitoring and Coaching was proven to be possible and nicely acquired by sufferers and healthcare professionals at University Medical Centre Utrecht, we goal to implement this e-health innovation nationwide, beginning with 10 ALS care groups in totally different rehabilitation settings unfold throughout the Netherlands.
This research focuses on the implementation course of and the consumer experiences with ALS Home-monitoring and Coaching of each sufferers and healthcare professionals. We will use a participatory motion research strategy, with the stakeholders concerned in all phases of the implementation course of. The implementation course of mannequin of Grol and Wensing was used to construction and assist planning, execution and analysis of the implementation technique. The anticipated limitations and facilitators can be explored and recognized in focus group settings utilizing the Theoretical Domains Framework. After that, every group will develop their very own motion plan with methods for resolve every barrier.
Dog Tongue Frozen Sections |
DF-105 |
Zyagen |
10 slides |
EUR 261 |
Cat Tongue Frozen Sections |
FF-105 |
Zyagen |
10 slides |
EUR 261 |
Rat Tongue Frozen Sections |
RF-105 |
Zyagen |
10 slides |
EUR 266 |
MiniPig Tongue Frozen Sections |
NF-105 |
Zyagen |
10 slides |
EUR 307 |
Rat WS Tongue Frozen Sections |
RF-105-WS |
Zyagen |
10 slides |
EUR 266 |
Mouse CD1 Tongue Frozen Sections |
MF-105 |
Zyagen |
10 slides |
EUR 266 |
Mouse BLC Tongue Frozen Sections |
MF-105-BLC |
Zyagen |
10 slides |
EUR 291 |
Mouse C57 Tongue Frozen Sections |
MF-105-C57 |
Zyagen |
10 slides |
EUR 291 |
Monkey Tongue Paraffin Sections, Rhesus |
UP-105 |
Zyagen |
10 slides |
EUR 280 |
Monkey Tongue Paraffin Sections, Cynomolgus |
KP-105 |
Zyagen |
10 slides |
EUR 280 |
Monkey Skin Frozen Sections, Rhesus |
UF-101 |
Zyagen |
10 slides |
EUR 307 |
Monkey Lung Frozen Sections, Rhesus |
UF-601 |
Zyagen |
10 slides |
EUR 307 |
Monkey Colon Frozen Sections, Rhesus |
UF-311 |
Zyagen |
10 slides |
EUR 307 |
Monkey Liver Frozen Sections, Rhesus |
UF-314 |
Zyagen |
10 slides |
EUR 307 |
Monkey Heart Frozen Sections, Rhesus |
UF-801 |
Zyagen |
10 slides |
EUR 307 |
Monkey Aorta Frozen Sections, Rhesus |
UF-807 |
Zyagen |
10 slides |
EUR 344 |
Monkey Rectum Frozen Sections, Rhesus |
UF-312 |
Zyagen |
10 slides |
EUR 307 |
Monkey Spleen Frozen Sections, Rhesus |
UF-701 |
Zyagen |
10 slides |
EUR 307 |
Monkey Thymus Frozen Sections, Rhesus |
UF-702 |
Zyagen |
10 slides |
EUR 344 |
Monkey Kidney Frozen Sections, Rhesus |
UF-901 |
Zyagen |
10 slides |
EUR 307 |
Monkey Adipose Frozen Sections, Rhesus |
UF-103 |
Zyagen |
10 slides |
EUR 344 |
Monkey Stomach Frozen Sections, Rhesus |
UF-303 |
Zyagen |
10 slides |
EUR 307 |
Monkey Bladder Frozen Sections, Rhesus |
UF-902 |
Zyagen |
10 slides |
EUR 344 |
Monkey Skin Frozen Sections, Cynomolgus |
KF-101 |
Zyagen |
10 slides |
EUR 307 |
Monkey Lung Frozen Sections, Cynomolgus |
KF-601 |
Zyagen |
10 slides |
EUR 307 |
Monkey Pancreas Frozen Sections, Rhesus |
UF-313 |
Zyagen |
10 slides |
EUR 307 |
Monkey Colon Frozen Sections, Cynomolgus |
KF-311 |
Zyagen |
10 slides |
EUR 307 |
Monkey Liver Frozen Sections, Cynomolgus |
KF-314 |
Zyagen |
10 slides |
EUR 307 |
Monkey Heart Frozen Sections, Cynomolgus |
KF-801 |
Zyagen |
10 slides |
EUR 307 |
Monkey Aorta Frozen Sections, Cynomolgus |
KF-807 |
Zyagen |
10 slides |
EUR 344 |
Monkey Brainstem Frozen Sections, Rhesus |
UF-215 |
Zyagen |
10 slides |
EUR 307 |
Monkey Esophagus Frozen Sections, Rhesus |
UF-301 |
Zyagen |
10 slides |
EUR 344 |
Monkey Diaphragm Frozen Sections, Rhesus |
UF-605 |
Zyagen |
10 slides |
EUR 307 |
Monkey Rectum Frozen Sections, Cynomolgus |
KF-312 |
Zyagen |
10 slides |
EUR 307 |
Monkey Spleen Frozen Sections, Cynomolgus |
KF-701 |
Zyagen |
10 slides |
EUR 307 |
Monkey Thymus Frozen Sections, Cynomolgus |
KF-702 |
Zyagen |
10 slides |
EUR 344 |
Monkey Kidney Frozen Sections, Cynomolgus |
KF-901 |
Zyagen |
10 slides |
EUR 307 |
Monkey Epididymis Frozen Sections, Rhesus |
UF-403 |
Zyagen |
10 slides |
EUR 344 |
Monkey Adipose Frozen Sections, Cynomolgus |
KF-103 |
Zyagen |
10 slides |
EUR 344 |
Monkey Stomach Frozen Sections, Cynomolgus |
KF-303 |
Zyagen |
10 slides |
EUR 307 |
Monkey Bladder Frozen Sections, Cynomolgus |
KF-902 |
Zyagen |
10 slides |
EUR 344 |
Monkey Pancreas Frozen Sections, Cynomolgus |
KF-313 |
Zyagen |
10 slides |
EUR 307 |
Monkey Brainstem Frozen Sections, Cynomolgus |
KF-215 |
Zyagen |
10 slides |
EUR 307 |
Monkey Esophagus Frozen Sections, Cynomolgus |
KF-301 |
Zyagen |
10 slides |
EUR 344 |
Monkey Diaphragm Frozen Sections, Cynomolgus |
KF-605 |
Zyagen |
10 slides |
EUR 307 |
Monkey Epididymis Frozen Sections, Cynomolgus |
KF-403 |
Zyagen |
10 slides |
EUR 344 |
Monkey Salivary Gland Frozen Sections, Rhesus |
UF-317 |
Zyagen |
10 slides |
EUR 307 |
Monkey Skeletal Muscle Frozen Sections, Rhesus |
UF-102 |
Zyagen |
10 slides |
EUR 307 |
Monkey Seminal Vesicle Frozen Sections, Rhesus |
UF407 |
Zyagen |
10 slides |
EUR 307 |
Monkey Brain Cerebellum Frozen Sections, Rhesus |
UF-202 |
Zyagen |
10 slides |
EUR 307 |
Monkey Salivary Gland Frozen Sections, Cynomolgus |
KF-317 |
Zyagen |
10 slides |
EUR 307 |
Monkey Skeletal Muscle Frozen Sections, Cynomolgus |
KF-102 |
Zyagen |
10 slides |
EUR 307 |
Monkey Seminal Vesicle Frozen Sections, Cynomolgus |
KF407 |
Zyagen |
10 slides |
EUR 307 |
Monkey Brain Cerebellum Frozen Sections, Cynomolgus |
KF-202 |
Zyagen |
10 slides |
EUR 307 |
Monkey Brain Cerebral Cortex Frozen Sections, Rhesus |
UF-210 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Ileum Frozen Sections, Rhesus |
UF-309 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Jejunum Frozen Sections, Rhesus |
UF-308 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Duodenum Frozen Sections, Rhesus |
UF-307 |
Zyagen |
10 slides |
EUR 319 |
Monkey Brain Cerebral Cortex Frozen Sections, Cynomolgus |
KF-210 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Ileum Frozen Sections, Cynomolgus |
KF-309 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Jejunum Frozen Sections, Cynomolgus |
KF-308 |
Zyagen |
10 slides |
EUR 307 |
Monkey Small Intestine, Duodenum Frozen Sections, Cynomolgus |
KF-307 |
Zyagen |
10 slides |
EUR 319 |
Dog Tongue paraffin Sections |
DP-105 |
Zyagen |
10 slides |
EUR 240 |
Cat Tongue Paraffin Sections |
FP-105 |
Zyagen |
10 slides |
EUR 240 |
Rat Tongue Paraffin Sections |
RP-105 |
Zyagen |
10 slides |
EUR 266 |
Human Tongue Paraffin Sections |
HP-105 |
Zyagen |
10 slides |
EUR 228 |
MiniPig Tongue Paraffin Sections |
Np-105 |
Zyagen |
10 slides |
EUR 307 |
Rat WS Tongue Paraffin Sections |
RP-105-WS |
Zyagen |
10 slides |
EUR 266 |
Mouse CD1 Tongue Paraffin Sections |
MP-105 |
Zyagen |
10 slides |
EUR 266 |
Mouse BLC Tongue Paraffin Sections |
MP-105-BLC |
Zyagen |
10 slides |
EUR 291 |
Mouse C57 Tongue Paraffin Sections |
MP-105-C57 |
Zyagen |
10 slides |
EUR 291 |
Human Tonsil Frozen Sections |
HF-707 |
Zyagen |
10Slides |
EUR 240 |
Rat Eye Frozen Sections |
RF-106 |
Zyagen |
10 slides |
EUR 266 |
Dog Skin Frozen Sections |
DF-101 |
Zyagen |
10 slides |
EUR 261 |
Dog Lung Frozen Sections |
DF-601 |
Zyagen |
10 slides |
EUR 261 |
Cat Lung Frozen Sections |
FF-601 |
Zyagen |
10 slides |
EUR 261 |
Pig Skin Frozen Sections |
PF-101 |
Zyagen |
10 slides |
EUR 261 |
Pig Lung Frozen Sections |
PF-601 |
Zyagen |
10 slides |
EUR 261 |
Rat Skin Frozen Sections |
RF-101 |
Zyagen |
10 slides |
EUR 228 |
Rat Lung Frozen Sections |
RF-601 |
Zyagen |
10 slides |
EUR 228 |
Dog Liver Frozen Sections |
DF-314 |
Zyagen |
10 slides |
EUR 261 |
Dog Ovary Frozen Sections |
DF-406 |
Zyagen |
10 slides |
EUR 261 |
Dog Heart Frozen Sections |
DF-801 |
Zyagen |
10 slides |
EUR 261 |
Cat Liver Frozen Sections |
FF-314 |
Zyagen |
10 slides |
EUR 261 |
Cat Ovary Frozen Sections |
FF-406 |
Zyagen |
10 slides |
EUR 261 |
Cat Heart Frozen Sections |
FF-801 |
Zyagen |
10 slides |
EUR 261 |
Pig Colon Frozen Sections |
PF-211 |
Zyagen |
10 slides |
EUR 261 |
Pig Liver Frozen Sections |
PF-314 |
Zyagen |
10 slides |
EUR 261 |
Pig Ovary Frozen Sections |
PF-406 |
Zyagen |
10 slides |
EUR 261 |
Pig Heart Frozen Sections |
PF-801 |
Zyagen |
10 slides |
EUR 261 |
Pig Aorta Frozen Sections |
PF-807 |
Zyagen |
10 slides |
EUR 261 |
Rat Cecum Frozen Sections |
RF-310 |
Zyagen |
10 slides |
EUR 228 |
Rat Colon Frozen Sections |
RF-311 |
Zyagen |
10 slides |
EUR 228 |
Rat Liver Frozen Sections |
RF-314 |
Zyagen |
10 slides |
EUR 228 |
Rat Ovary Frozen Sections |
RF-406 |
Zyagen |
10 slides |
EUR 228 |
Rat Penis Frozen Sections |
RF-416 |
Zyagen |
10 slides |
EUR 228 |
Rat Aorta Frozen Sections |
RF-807 |
Zyagen |
10 slides |
EUR 266 |
Human Skin Frozen Sections |
HF-101 |
Zyagen |
10slides |
EUR 240 |
Human Lung Frozen Sections |
HF-601 |
Zyagen |
10slides |
EUR 240 |
Human Vein Frozen Sections |
HF-821 |
Zyagen |
10slides |
EUR 240 |
Dog Rectum Frozen Sections |
DF-312 |
Zyagen |
10 slides |
EUR 261 |
Dog Testis Frozen Sections |
DF-401 |
Zyagen |
10 slides |
EUR 261 |
Dog Spleen Frozen Sections |
DF-701 |
Zyagen |
10 slides |
EUR 261 |
Dog Thymus Frozen Sections |
DF-702 |
Zyagen |
10 slides |
EUR 261 |
Dog Kidney Frozen Sections |
DF-901 |
Zyagen |
10 slides |
EUR 261 |
Cat Rectum Frozen Sections |
FF-312 |
Zyagen |
10 slides |
EUR 261 |
Cat Testis Frozen Sections |
FF-401 |
Zyagen |
10 slides |
EUR 261 |
Cat Spleen Frozen Sections |
FF-701 |
Zyagen |
10 slides |
EUR 261 |
Cat Thymus Frozen Sections |
FF-702 |
Zyagen |
10 slides |
EUR 261 |
Cat Kidney Frozen Sections |
FF-901 |
Zyagen |
10 slides |
EUR 261 |
Pig Testis Frozen Sections |
PF-401 |
Zyagen |
10 slides |
EUR 261 |
Pig Uterus Frozen Sections |
PF-411 |
Zyagen |
10 slides |
EUR 261 |
Pig Pineal Frozen Sections |
PF-505 |
Zyagen |
10 slides |
EUR 261 |
Pig Spleen Frozen Sections |
PF-701 |
Zyagen |
10 slides |
EUR 261 |
Pig Thymus Frozen Sections |
PF-702 |
Zyagen |
10 slides |
EUR 261 |
Pig Kidney Frozen Sections |
PF-901 |
Zyagen |
10 slides |
EUR 261 |
Rat Rectum Frozen Sections |
RF-312 |
Zyagen |
10 slides |
EUR 228 |
Rat Testis Frozen Sections |
RF-401 |
Zyagen |
10 slides |
EUR 228 |
Rat Vagina Frozen Sections |
RF-412 |
Zyagen |
10 slides |
EUR 228 |
Rat Spleen Frozen Sections |
RF-701 |
Zyagen |
10 slides |
EUR 228 |
Rat Thymus Frozen Sections |
RF-702 |
Zyagen |
10 slides |
EUR 228 |
Rat Kidney Frozen Sections |
RF-901 |
Zyagen |
10 slides |
EUR 228 |
Sheep Skin Frozen Sections |
SF-101 |
Zyagen |
10 slides |
EUR 261 |
Sheep Lung Frozen Sections |
SF-601 |
Zyagen |
10 slides |
EUR 261 |
Human Colon Frozen Sections |
HF-311 |
Zyagen |
10slides |
EUR 240 |
Human Liver Frozen Sections |
HF-314 |
Zyagen |
10 slides |
EUR 240 |
Human Ovary Frozen Sections |
HF-406 |
Zyagen |
10slides |
EUR 240 |
Human Heart Frozen Sections |
HF-801 |
Zyagen |
10slides |
EUR 240 |
Bovine Skin Frozen Sections |
BF-101 |
Zyagen |
10 slides |
EUR 261 |
Bovine Lung Frozen Sections |
BF-601 |
Zyagen |
10 slides |
EUR 261 |
Dog Stomach Frozen Sections |
DF-302 |
Zyagen |
10 slides |
EUR 261 |
Dog Bladder Frozen Sections |
DF-902 |
Zyagen |
10 slides |
EUR 261 |
Equine Skin Frozen Sections |
EF-101 |
Zyagen |
10 slides |
EUR 261 |
Equine Lung Frozen Sections |
EF-601 |
Zyagen |
10 slides |
EUR 261 |
Cat Stomach Frozen Sections |
FF-302 |
Zyagen |
10 slides |
EUR 261 |
Cat Bladder Frozen Sections |
FF-902 |
Zyagen |
10 slides |
EUR 261 |
Pig Stomach Frozen Sections |
PF-302 |
Zyagen |
10 slides |
EUR 261 |
Pig Adrenal Frozen Sections |
PF-501 |
Zyagen |
10 slides |
EUR 261 |
Pig Thyroid Frozen Sections |
PF-503 |
Zyagen |
10 slides |
EUR 261 |
Pig Bladder Frozen Sections |
PF-902 |
Zyagen |
10 slides |
EUR 261 |
Rat Oviduct Frozen Sections |
RF-410 |
Zyagen |
10 slides |
EUR 228 |
Rat Adrenal Frozen Sections |
RF-501 |
Zyagen |
10 slides |
EUR 266 |
Rat Thyroid Frozen Sections |
RF-503 |
Zyagen |
10 slides |
EUR 266 |
The groups will embrace 5-10 ALS sufferers with whom they are going to check their implementation plan and present care with ALS Home-monitoring and Coaching for about Three months. Afterwards, the implementation and the consumer experiences can be evaluated with digital surveys primarily based on the analysis framework of Proctor (e.g., acceptability, adoption, appropriateness).