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[Embedding research into health services in Latin America and the Caribbean: experiences and challenges of the Technical Support CenterExperiências e desafios do Centro de Apoio Técnico na pesquisa integrada aos serviços na América Latina e Caribe]

This article describes the principal fashions for embedding research and the profitable experiences and challenges confronted in joint work by researchers and decisionmakers who participated in the Embedding Research for the Sustainable Development Goals (ER-SDG) initiative, and the expertise of the Technical Support Center. In June 2018, funding was granted to 13 pre-selected research initiatives from 11 middle- and low-income international locations in Latin America and the Caribbean (Argentina, Bolivia, Brazil, Colombia, Dominican Republic, Ecuador, Guatemala, Guyana, Haiti, Paraguay, and Peru).

The initiatives targeted on the system-, policy-, or program-level adjustments required to enhance health and construct on the joint work of researchers and decisionmakers, with a view to bringing collectively proof manufacturing and decision-making in health methods and services. The Technical Support Center supported and guided the manufacturing of high quality outcomes helpful for decision-making. This expertise confirmed the worth of initiatives similar to ER-SDG in consolidating bridges between research on the implementation of health insurance policies, applications, and methods, and the officers accountable for working health-related applications, services, and interventions.

Children 8-17 years of age and their caregivers accomplished PROMIS measures (bodily operate, melancholy, peer relationships, ache interference, and anger) between 6 months and 15 years after harm. Self- and proxy-report scores had been in contrast utilizing Wilcoxon signal rank check, Cohen’s impact dimension, and intraclass correlation coefficients (ICC) and by settlement throughout severity of signs primarily based on really helpful cutoffs. Ordinary least squares regression analyses examined child- (self-report rating, age, gender, and ethnicity) and proxy-related (relationship to baby) elements related to rating variations.

Two hundred and seventy 4 child-caregiver pairs accomplished the PROMIS measures. Mean baby age was 13.0 (SD:3) years. Caregivers reported considerably worse scores than the baby on bodily operate, ache, and anger (all p ≤ 0.01). The impact sizes had been small throughout all domains besides bodily operate. Similarly, ICCs had been all of average settlement. The proportion of dyads in settlement by severity teams was excessive with solely 5%-9% of pairs discordant. Only increased self-report rating was related (all p < 0.05) with better variations throughout all domains in regression analyses.

Research Synthesis, HIV Prevention Response, and Public Health: CDC’s HIV/AIDS Prevention Research Synthesis Project

Research synthesis, by qualitative or quantitative systematic opinions, permits for integrating outcomes of major research to enhance public health. We examined greater than 2 many years of work in HIV prevention by the Centers for Disease Control and Prevention’s (CDC’s) HIV/AIDS Prevention Research Synthesis (PRS) Project. We describe the context and contributions of research synthesis, together with systematic opinions and meta-analyses, by the expertise of the PRS Project.
We reviewed PRS Project publications and merchandise and summarized PRS contributions from 1996 to July 2020 in four areas: synthesis of interventions and epidemiologic research, synthesis strategies, prevention applications, and prevention coverage. PRS Project publications summarized threat behaviors and results of prevention interventions (eg, altering one’s notion of threat, educating condom negotiation abilities) throughout populations in danger for HIV an infection and intervention approaches (eg, one-on-one or group conferences) as the HIV/AIDS epidemic and science developed.
We used the PRS Project cumulative database and intervention efficacy opinions to contribute to prevention applications and insurance policies by identification of evidence-based interventions and growth of program steerage. Subject matter consultants and scientific proof knowledgeable PRS Project merchandise and contributions, which had been carried out by strategic programmatic partnerships. The impact of the PRS Project was seemingly facilitated by alternatives to immediately affect program and coverage as a result of of connections with different research translation actions and program and coverage choice making inside CDC.
Models of Governance for Innovation in Medicine and Health Research

Implementation and analysis of an e-health innovation for customized take care of sufferers with amyotrophic lateral sclerosis (ALS): protocol for a participatory motion research examine

In the absence of a treatment for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative illness, remedy consists of symptomatic administration by a multidisciplinary healthcare group and is especially geared toward optimizing sufferers’ high quality of life. Because the course of the illness is usually erratic and varies between sufferers, it’s crucial for sufferers with ALS to be carefully monitored. E-health improvements that may monitor illness development remotely have nice potential to tailor the care to the wants of particular person sufferers with ALS.
Therefore, the e-health innovation “ALS Home-monitoring and Coaching” was developed using a user-centered design course of and carried out at the University Medical Center Utrecht, the Netherlands in 2017. Because ALS Home-monitoring and Coaching was proven to be possible and nicely acquired by sufferers and healthcare professionals at University Medical Centre Utrecht, we goal to implement this e-health innovation nationwide, beginning with 10 ALS care groups in totally different rehabilitation settings unfold throughout the Netherlands.
This research focuses on the implementation course of and the consumer experiences with ALS Home-monitoring and Coaching of each sufferers and healthcare professionals. We will use a participatory motion research strategy, with the stakeholders concerned in all phases of the implementation course of. The implementation course of mannequin of Grol and Wensing was used to construction and assist planning, execution and analysis of the implementation technique. The anticipated limitations and facilitators can be explored and recognized in focus group settings utilizing the Theoretical Domains Framework. After that, every group will develop their very own motion plan with methods for resolve every barrier.

Dog Tongue Frozen Sections

DF-105 10 slides
EUR 261

Cat Tongue Frozen Sections

FF-105 10 slides
EUR 261

Rat Tongue Frozen Sections

RF-105 10 slides
EUR 266

MiniPig Tongue Frozen Sections

NF-105 10 slides
EUR 307

Rat WS Tongue Frozen Sections

RF-105-WS 10 slides
EUR 266

Mouse CD1 Tongue Frozen Sections

MF-105 10 slides
EUR 266

Mouse BLC Tongue Frozen Sections

MF-105-BLC 10 slides
EUR 291

Mouse C57 Tongue Frozen Sections

MF-105-C57 10 slides
EUR 291

Monkey Tongue Paraffin Sections, Rhesus

UP-105 10 slides
EUR 280

Monkey Tongue Paraffin Sections, Cynomolgus

KP-105 10 slides
EUR 280

Monkey Skin Frozen Sections, Rhesus

UF-101 10 slides
EUR 307

Monkey Lung Frozen Sections, Rhesus

UF-601 10 slides
EUR 307

Monkey Colon Frozen Sections, Rhesus

UF-311 10 slides
EUR 307

Monkey Liver Frozen Sections, Rhesus

UF-314 10 slides
EUR 307

Monkey Heart Frozen Sections, Rhesus

UF-801 10 slides
EUR 307

Monkey Aorta Frozen Sections, Rhesus

UF-807 10 slides
EUR 344

Monkey Rectum Frozen Sections, Rhesus

UF-312 10 slides
EUR 307

Monkey Spleen Frozen Sections, Rhesus

UF-701 10 slides
EUR 307

Monkey Thymus Frozen Sections, Rhesus

UF-702 10 slides
EUR 344

Monkey Kidney Frozen Sections, Rhesus

UF-901 10 slides
EUR 307

Monkey Adipose Frozen Sections, Rhesus

UF-103 10 slides
EUR 344

Monkey Stomach Frozen Sections, Rhesus

UF-303 10 slides
EUR 307

Monkey Bladder Frozen Sections, Rhesus

UF-902 10 slides
EUR 344

Monkey Skin Frozen Sections, Cynomolgus

KF-101 10 slides
EUR 307

Monkey Lung Frozen Sections, Cynomolgus

KF-601 10 slides
EUR 307

Monkey Pancreas Frozen Sections, Rhesus

UF-313 10 slides
EUR 307

Monkey Colon Frozen Sections, Cynomolgus

KF-311 10 slides
EUR 307

Monkey Liver Frozen Sections, Cynomolgus

KF-314 10 slides
EUR 307

Monkey Heart Frozen Sections, Cynomolgus

KF-801 10 slides
EUR 307

Monkey Aorta Frozen Sections, Cynomolgus

KF-807 10 slides
EUR 344

Monkey Brainstem Frozen Sections, Rhesus

UF-215 10 slides
EUR 307

Monkey Esophagus Frozen Sections, Rhesus

UF-301 10 slides
EUR 344

Monkey Diaphragm Frozen Sections, Rhesus

UF-605 10 slides
EUR 307

Monkey Rectum Frozen Sections, Cynomolgus

KF-312 10 slides
EUR 307

Monkey Spleen Frozen Sections, Cynomolgus

KF-701 10 slides
EUR 307

Monkey Thymus Frozen Sections, Cynomolgus

KF-702 10 slides
EUR 344

Monkey Kidney Frozen Sections, Cynomolgus

KF-901 10 slides
EUR 307

Monkey Epididymis Frozen Sections, Rhesus

UF-403 10 slides
EUR 344

Monkey Adipose Frozen Sections, Cynomolgus

KF-103 10 slides
EUR 344

Monkey Stomach Frozen Sections, Cynomolgus

KF-303 10 slides
EUR 307

Monkey Bladder Frozen Sections, Cynomolgus

KF-902 10 slides
EUR 344

Monkey Pancreas Frozen Sections, Cynomolgus

KF-313 10 slides
EUR 307

Monkey Brainstem Frozen Sections, Cynomolgus

KF-215 10 slides
EUR 307

Monkey Esophagus Frozen Sections, Cynomolgus

KF-301 10 slides
EUR 344

Monkey Diaphragm Frozen Sections, Cynomolgus

KF-605 10 slides
EUR 307

Monkey Epididymis Frozen Sections, Cynomolgus

KF-403 10 slides
EUR 344

Monkey Salivary Gland Frozen Sections, Rhesus

UF-317 10 slides
EUR 307

Monkey Skeletal Muscle Frozen Sections, Rhesus

UF-102 10 slides
EUR 307

Monkey Seminal Vesicle Frozen Sections, Rhesus

UF407 10 slides
EUR 307

Monkey Brain Cerebellum Frozen Sections, Rhesus

UF-202 10 slides
EUR 307

Monkey Salivary Gland Frozen Sections, Cynomolgus

KF-317 10 slides
EUR 307

Monkey Skeletal Muscle Frozen Sections, Cynomolgus

KF-102 10 slides
EUR 307

Monkey Seminal Vesicle Frozen Sections, Cynomolgus

KF407 10 slides
EUR 307

Monkey Brain Cerebellum Frozen Sections, Cynomolgus

KF-202 10 slides
EUR 307

Monkey Brain Cerebral Cortex Frozen Sections, Rhesus

UF-210 10 slides
EUR 307

Monkey Small Intestine, Ileum Frozen Sections, Rhesus

UF-309 10 slides
EUR 307

Monkey Small Intestine, Jejunum Frozen Sections, Rhesus

UF-308 10 slides
EUR 307

Monkey Small Intestine, Duodenum Frozen Sections, Rhesus

UF-307 10 slides
EUR 319

Monkey Brain Cerebral Cortex Frozen Sections, Cynomolgus

KF-210 10 slides
EUR 307

Monkey Small Intestine, Ileum Frozen Sections, Cynomolgus

KF-309 10 slides
EUR 307

Monkey Small Intestine, Jejunum Frozen Sections, Cynomolgus

KF-308 10 slides
EUR 307

Monkey Small Intestine, Duodenum Frozen Sections, Cynomolgus

KF-307 10 slides
EUR 319

Dog Tongue paraffin Sections

DP-105 10 slides
EUR 240

Cat Tongue Paraffin Sections

FP-105 10 slides
EUR 240

Rat Tongue Paraffin Sections

RP-105 10 slides
EUR 266

Human Tongue Paraffin Sections

HP-105 10 slides
EUR 228

MiniPig Tongue Paraffin Sections

Np-105 10 slides
EUR 307

Rat WS Tongue Paraffin Sections

RP-105-WS 10 slides
EUR 266

Mouse CD1 Tongue Paraffin Sections

MP-105 10 slides
EUR 266

Mouse BLC Tongue Paraffin Sections

MP-105-BLC 10 slides
EUR 291

Mouse C57 Tongue Paraffin Sections

MP-105-C57 10 slides
EUR 291

Human Tonsil Frozen Sections

HF-707 10Slides
EUR 240

Rat Eye Frozen Sections

RF-106 10 slides
EUR 266

Dog Skin Frozen Sections

DF-101 10 slides
EUR 261

Dog Lung Frozen Sections

DF-601 10 slides
EUR 261

Cat Lung Frozen Sections

FF-601 10 slides
EUR 261

Pig Skin Frozen Sections

PF-101 10 slides
EUR 261

Pig Lung Frozen Sections

PF-601 10 slides
EUR 261

Rat Skin Frozen Sections

RF-101 10 slides
EUR 228

Rat Lung Frozen Sections

RF-601 10 slides
EUR 228

Dog Liver Frozen Sections

DF-314 10 slides
EUR 261

Dog Ovary Frozen Sections

DF-406 10 slides
EUR 261

Dog Heart Frozen Sections

DF-801 10 slides
EUR 261

Cat Liver Frozen Sections

FF-314 10 slides
EUR 261

Cat Ovary Frozen Sections

FF-406 10 slides
EUR 261

Cat Heart Frozen Sections

FF-801 10 slides
EUR 261

Pig Colon Frozen Sections

PF-211 10 slides
EUR 261

Pig Liver Frozen Sections

PF-314 10 slides
EUR 261

Pig Ovary Frozen Sections

PF-406 10 slides
EUR 261

Pig Heart Frozen Sections

PF-801 10 slides
EUR 261

Pig Aorta Frozen Sections

PF-807 10 slides
EUR 261

Rat Cecum Frozen Sections

RF-310 10 slides
EUR 228

Rat Colon Frozen Sections

RF-311 10 slides
EUR 228

Rat Liver Frozen Sections

RF-314 10 slides
EUR 228

Rat Ovary Frozen Sections

RF-406 10 slides
EUR 228

Rat Penis Frozen Sections

RF-416 10 slides
EUR 228

Rat Aorta Frozen Sections

RF-807 10 slides
EUR 266

Human Skin Frozen Sections

HF-101 10slides
EUR 240

Human Lung Frozen Sections

HF-601 10slides
EUR 240

Human Vein Frozen Sections

HF-821 10slides
EUR 240

Dog Rectum Frozen Sections

DF-312 10 slides
EUR 261

Dog Testis Frozen Sections

DF-401 10 slides
EUR 261

Dog Spleen Frozen Sections

DF-701 10 slides
EUR 261

Dog Thymus Frozen Sections

DF-702 10 slides
EUR 261

Dog Kidney Frozen Sections

DF-901 10 slides
EUR 261

Cat Rectum Frozen Sections

FF-312 10 slides
EUR 261

Cat Testis Frozen Sections

FF-401 10 slides
EUR 261

Cat Spleen Frozen Sections

FF-701 10 slides
EUR 261

Cat Thymus Frozen Sections

FF-702 10 slides
EUR 261

Cat Kidney Frozen Sections

FF-901 10 slides
EUR 261

Pig Testis Frozen Sections

PF-401 10 slides
EUR 261

Pig Uterus Frozen Sections

PF-411 10 slides
EUR 261

Pig Pineal Frozen Sections

PF-505 10 slides
EUR 261

Pig Spleen Frozen Sections

PF-701 10 slides
EUR 261

Pig Thymus Frozen Sections

PF-702 10 slides
EUR 261

Pig Kidney Frozen Sections

PF-901 10 slides
EUR 261

Rat Rectum Frozen Sections

RF-312 10 slides
EUR 228

Rat Testis Frozen Sections

RF-401 10 slides
EUR 228

Rat Vagina Frozen Sections

RF-412 10 slides
EUR 228

Rat Spleen Frozen Sections

RF-701 10 slides
EUR 228

Rat Thymus Frozen Sections

RF-702 10 slides
EUR 228

Rat Kidney Frozen Sections

RF-901 10 slides
EUR 228

Sheep Skin Frozen Sections

SF-101 10 slides
EUR 261

Sheep Lung Frozen Sections

SF-601 10 slides
EUR 261

Human Colon Frozen Sections

HF-311 10slides
EUR 240

Human Liver Frozen Sections

HF-314 10 slides
EUR 240

Human Ovary Frozen Sections

HF-406 10slides
EUR 240

Human Heart Frozen Sections

HF-801 10slides
EUR 240

Bovine Skin Frozen Sections

BF-101 10 slides
EUR 261

Bovine Lung Frozen Sections

BF-601 10 slides
EUR 261

Dog Stomach Frozen Sections

DF-302 10 slides
EUR 261

Dog Bladder Frozen Sections

DF-902 10 slides
EUR 261

Equine Skin Frozen Sections

EF-101 10 slides
EUR 261

Equine Lung Frozen Sections

EF-601 10 slides
EUR 261

Cat Stomach Frozen Sections

FF-302 10 slides
EUR 261

Cat Bladder Frozen Sections

FF-902 10 slides
EUR 261

Pig Stomach Frozen Sections

PF-302 10 slides
EUR 261

Pig Adrenal Frozen Sections

PF-501 10 slides
EUR 261

Pig Thyroid Frozen Sections

PF-503 10 slides
EUR 261

Pig Bladder Frozen Sections

PF-902 10 slides
EUR 261

Rat Oviduct Frozen Sections

RF-410 10 slides
EUR 228

Rat Adrenal Frozen Sections

RF-501 10 slides
EUR 266

Rat Thyroid Frozen Sections

RF-503 10 slides
EUR 266
The groups will embrace 5-10 ALS sufferers with whom they are going to check their implementation plan and present care with ALS Home-monitoring and Coaching for about Three months. Afterwards, the implementation and the consumer experiences can be evaluated with digital surveys primarily based on the analysis framework of Proctor (e.g., acceptability, adoption, appropriateness).