Aedes-borne disease outbreaks in West Africa: A call for enhanced surveillance.

Arboviruses transmitted by Aedes mosquitoes are a growing global concern; however, there remain large gaps in surveillance of both arboviruses and their vectors in West Africa. We reviewed over 50 years of data including outbreak reports, peer-reviewed literature, and prior data compilations describing Zika, dengue, and chikungunya, and their vectors in West Africa. Large outbreaks of dengue, Zika, and chikungunya have recently occurred in the region with over 27,000 cases of Aedes-borne disease documented since 2007.

Recent arboviral outbreaks have become more concentrated in urban areas, and Aedes albopictus, a relatively new arrival in the region, has emerged as an important vector in several areas. Seroprevalence surveys suggest reported cases are a gross underestimate of the underlying arboviral disease burden.

hsa-miR-652 Primers

MPH01954 150 ul / 10 uM
EUR 121

mmu-miR-652-3p Primers

MPM01554 150 ul / 10 uM
EUR 121

mmu-miR-652-5p Primers

MPM01555 150 ul / 10 uM
EUR 121

rno-miR-652-3p Primers

MPR00801 150 ul / 10 uM
EUR 176

rno-miR-652-5p Primers

MPR00802 150 ul / 10 uM
EUR 176

hsa-miR-652 miRNA Inhibitor

MIH03348 2 x 5.0 nmol
EUR 176

mmu-miR-652 miRNA Inhibitor

MIM02429 2 x 5.0 nmol
EUR 176

rno??miR-652 miRNA Inhibitor

MIR01748 2 x 5.0 nmol
EUR 176

hsa-miR-652 miRNA Antagomir

MNH03348 2 x 5.0 nmol
EUR 329

mmu-miR-652 miRNA Antagomir

MNM02429 2 x 5.0 nmol
EUR 329

rno??miR-652 miRNA Antagomir

MNR01748 2 x 5.0 nmol
EUR 329

hsa-miR-652-3p Primers

MPH03439 150 ul / 10 uM
EUR 121

hsa-miR-652-5p Primers

MPH03440 150 ul / 10 uM
EUR 121

Zinc Finger Protein 652 (Zfp652) Antibody

abx431848-200ul 200 ul
EUR 286

Zinc Finger Protein 652 (ZNF652) Antibody

abx433461-200ul 200 ul
EUR 384

hsa-miR-652-3p miRNA Inhibitor

MIH03349 2 x 5.0 nmol
EUR 176

hsa-miR-652-5p miRNA Inhibitor

MIH03350 2 x 5.0 nmol
EUR 176

mmu-miR-652-3p miRNA Inhibitor

MIM02430 2 x 5.0 nmol
EUR 176

mmu-miR-652-5p miRNA Inhibitor

MIM02431 2 x 5.0 nmol
EUR 176

rno-miR-652-3p miRNA Inhibitor

MIR01749 2 x 5.0 nmol
EUR 176

rno-miR-652-5p miRNA Inhibitor

MIR01750 2 x 5.0 nmol
EUR 176

hsa-miR-652-3p miRNA Antagomir

MNH03349 2 x 5.0 nmol
EUR 329

hsa-miR-652-5p miRNA Antagomir

MNH03350 2 x 5.0 nmol
EUR 329

mmu-miR-652-3p miRNA Antagomir

MNM02430 2 x 5.0 nmol
EUR 329

mmu-miR-652-5p miRNA Antagomir

MNM02431 2 x 5.0 nmol
EUR 329

rno-miR-652-3p miRNA Antagomir

MNR01749 2 x 5.0 nmol
EUR 329

rno-miR-652-5p miRNA Antagomir

MNR01750 2 x 5.0 nmol
EUR 329

ROR 2 Recombinant Protein

96-652 0.05 mg
EUR 542.75
Description: Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

DKK-3 Recombinant Protein

40-652 2 ug
EUR 259.25
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-L1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant Human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, Human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

G6PD Recombinant Protein

91-652 0.05 mg
EUR 710.75
Description: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

Fc gamma RI Recombinant Protein

92-652 0.05 mg
EUR 401
Description: CD64 (Fc gamma RI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors Fc gamma RII and Fc gamma RIII. It is normally expressed on the surfaces of monocytes and macrophages.

Cynomolgus Her2 Protein (Thr 23-Thr 652)

VAng-1654Lsx-100g 100 µg
EUR 875
Description: Cynomolgus Her2 is expressed in human 293 cells. (Uniprot ID: XP_005584091.2)

Cynomolgus Her2 Protein (Thr 23-Thr 652)

VAng-1654Lsx-1mg 1 mg
EUR 5494
Description: Cynomolgus Her2 is expressed in human 293 cells. (Uniprot ID: XP_005584091.2)

Human Her2 Protein (Thr 23-Thr 652)

VAng-1711Lsx-500g 500 µg
EUR 3349
Description: Human Her2 is expressed in human 293 cells. (Uniprot ID: P04626-1)

Human Her2 Protein (Thr 23-Thr 652)

VAng-1711Lsx-50g 50 µg
EUR 930
Description: Human Her2 is expressed in human 293 cells. (Uniprot ID: P04626-1)

Human Her2 Protein (Thr 23-Thr 652) [Fc]

VAng-1712Lsx-100g 100 µg
EUR 875
Description: Human Her2, Mouse IgG2a Fc tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

Human Her2 Protein (Thr 23-Thr 652) [Fc]

VAng-1712Lsx-1mg 1 mg
EUR 5494
Description: Human Her2, Mouse IgG2a Fc tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1713Lsx-100g 100 µg
EUR 1013
Description: Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: AAA75493)

Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1713Lsx-1mg 1 mg
EUR 6319
Description: Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: AAA75493)

Human Her2 Protein (Thr 23-Thr 652) [Strep]

VAng-1715Lsx-50g 50 µg
EUR 1013
Description: Human Her2, Strep tag, is expressed in human 293 cells. (Uniprot ID: AAA75493)

Recombinant Mycobacterium Tuberculosis narX Protein (aa 1-652)

VAng-Yyj0532-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Nitrate reductase-like protein narX (narX), recombinant protein.

Recombinant Pichia pastoris SLX4 Protein (aa 1-652)

VAng-Cr6677-inquire inquire Ask for price
Description: Pichia pastoris (strain GS115 / ATCC 20864) Structure-specific endonuclease subunit SLX4 (SLX4), recombinant protein.

Recombinant Streptococcus Pneumoniae aliB Protein (aa 1-652)

VAng-Cr7767-inquire inquire Ask for price
Description: Streptococcus Pneumoniae Oligopeptide-binding protein AliB (aliB), recombinant protein.

Recombinant Streptococcus Pneumoniae ftsH Protein (aa 1-652)

VAng-Cr7814-1mgEcoli 1 mg (E. coli)
EUR 3198
Description: Streptococcus Pneumoniae ATP-dependent zinc metalloprotease FtsH (ftsH), recombinant protein.

Recombinant Clostridium Perfringens tetP Protein (aa 1-652)

VAng-Lsx00882-inquire inquire Ask for price
Description: Clostridium Perfringens Tetracycline resistance protein tetP, recombinant protein.

Recombinant Human ERBB2 Protein (aa 1-652) [AVI]

VAng-Cr3983-inquire inquire Ask for price
Description: Recombinant Human ERBB2 Protein (Met1-Thr652) fused with a AVI tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 72.6 kDa. (Accession ID: NP_004439.2)

Recombinant Rhesus ERBB2 Protein (aa 1-652) [Fc]

VAng-Cr3985-100g 100 µg
EUR 1687
Description: Recombinant Rhesus ERBB2 Protein (Met 1-Thr 652) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.3 kDa. (Accession ID: XP_001090430.1)

Recombinant Rhesus ERBB2 Protein (aa 1-652) [Fc]

VAng-Cr3985-50g 50 µg
EUR 1027
Description: Recombinant Rhesus ERBB2 Protein (Met 1-Thr 652) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.3 kDa. (Accession ID: XP_001090430.1)

Recombinant Human ERBB2 Protein (aa 1-652) [Fc]

VAng-Cr3987-100g 100 µg
EUR 1687
Description: Recombinant Human ERBB2 Protein (Met 1-Thr 652) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.1 kDa. (Accession ID: NP_004439.2)

Recombinant Human ERBB2 Protein (aa 1-652) [Fc]

VAng-Cr3987-50g 50 µg
EUR 1027
Description: Recombinant Human ERBB2 Protein (Met 1-Thr 652) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.1 kDa. (Accession ID: NP_004439.2)

Recombinant Mouse ErbB4 Protein (aa 1-652) [His]

VAng-Cr3997-100g 100 µg
EUR 1687
Description: Recombinant Mouse ErbB4 Protein (Met1-Leu652) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.5 kDa. (Accession ID: Q99P91)

Recombinant Mouse ErbB4 Protein (aa 1-652) [His]

VAng-Cr3997-50g 50 µg
EUR 1027
Description: Recombinant Mouse ErbB4 Protein (Met1-Leu652) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.5 kDa. (Accession ID: Q99P91)

Recombinant Schizosaccharomyces Pombe ssp1 Protein (aa 1-652)

VAng-Yyj6250-inquire inquire Ask for price
Description: Schizosaccharomyces Pombe (strain 972 / ATCC 24843) (Fission yeast) Serine/threonine-protein kinase ssp1 (ssp1), recombinant protein.

Human Zinc finger protein 652, ZNF652 ELISA KIT

ELI-51280h 96 Tests
EUR 824

Mouse Zinc finger protein 652, Znf652 ELISA KIT

ELI-51588m 96 Tests
EUR 865

Human pre-microRNA Expression Construct Lenti-miR-652

PMIRH652AA-1 Bacterial Streak
EUR 684

Human pre-microRNA Expression Construct Lenti-miR-652

PMIRH652PA-1 Bacterial Streak
EUR 684

Rabbit Anti-Human AR (aa 648-652) Polyclonal Antibody

CPB-1013RH 100 ul
EUR 460

Biotinylated Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1611Lsx-200g 200 µg
EUR 3830
Description: Biotinylated Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: AAA75493)

Biotinylated Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1611Lsx-25g 25 µg
EUR 928
Description: Biotinylated Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: AAA75493)

Cynomolgus Her2 Protein (Thr 23-Thr 652) [His] [Avi]

VAng-1655Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Cynomolgus Her2, Hia tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: XP_005584091.2)

Cynomolgus Her2 Protein (Thr 23-Thr 652) [His] [Avi]

VAng-1655Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Cynomolgus Her2, Hia tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: XP_005584091.2)

Human Her2 Protein (Thr 23-Thr 652) [His] [Avi]

VAng-1714Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human Her2, His tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

Human Her2 Protein (Thr 23-Thr 652) [His] [Avi]

VAng-1714Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human Her2, His tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

FITC-Labeled Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1665Lsx-200g 200 µg
EUR 5219
Description: FITC-Labeled Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

FITC-Labeled Human Her2 Protein (Thr 23-Thr 652) [His]

VAng-1665Lsx-25g 25 µg
EUR 848
Description: FITC-Labeled Human Her2, His tag, is expressed in human 293 cells. (Uniprot ID: P04626-1)

Recombinant Yersinia Enterocolitica acs Protein (aa 1-652) (strain 8081)

VAng-Wyb1361-inquire inquire Ask for price
Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) Acetyl-coenzyme A synthetase, recombinant protein.

Rabbit Anti-human Her2/Erbb2/Neu (1-652) protein IgG

HER32-A 100 ul
EUR 482

Anti-ACVR2B (Bimagrumab)-MC-MMAF ADC

ADC-W-652 1mg Ask for price
Description: This ADC product is comprised of an anti-ACVR2B monoclonal antibody conjugated via a MC linker to MMAF

Anti-Hu CD90 APC

1A-652-T025 25 tests
EUR 140

Anti-Hu CD90 APC

1A-652-T100 100 tests
EUR 240

Anti-Hu CD90 FITC

1F-652-T025 25 tests
EUR 122

Anti-Hu CD90 FITC

1F-652-T100 100 tests
EUR 204

Anti-Hu CD90 PE

1P-652-T025 25 tests
EUR 140

Anti-Hu CD90 PE

1P-652-T100 100 tests
EUR 240

Anti-Hu CD90 Purified Azide Free

10-652-C025 0.025 mg
EUR 99

Anti-Hu CD90 Purified Azide Free

10-652-C100 0.1 mg
EUR 158

Anti-Hu CD90 APC-Cy7

T4-652-T100 100 tests
EUR 268

Anti-Hu CD90 PE-Cy5

T8-652-T025 25 tests
EUR 140

Anti-Hu CD90 PE-Cy5

T8-652-T100 100 tests
EUR 240

Rabbit mono anti-human Her2/Erbb2/Neu (1-652) protein IgG

HER31-M 100 ul
EUR 482

Rabbit Anti-monkey/rhesus Her2/Erbb2/Neu (1-652) protein IgG

HER34-A 100 ul
EUR 482

Recombinant (HEK) human Her2/Erbb2/Neu (1-652)-hIgG-Fc fusion protein

HER21-R-10 10 ug
EUR 408

Recombinant (HEK) human Her2/Erbb2/Neu (23-652)-His-tag fusion protein

HER23-R-10 10 ug
EUR 408

Mouse mono anti-monkey/rhesus Her2/Erbb2/Neu (1-652) protein IgG

HER33-M 100 ul
EUR 482

Recombinant (HEK) monkey/rhesus Her2/Erbb2/Neu (1-652)-His-tag fusion protein

HER29-R-10 10 ug
EUR 408

Recombinant (HEK) monkey/rhesus Her2/Erbb2/Neu (1-652)-hIgG1-Fc fusion protein

HER30-R-10 10 ug
EUR 408

Recombinant (HEK) human Her2/Erbb2/Neu (1-652)-Flag tag (DDDDK) fusion protein

HER36-R-10 10 ug
EUR 408

Recombinant (HEK) human Her2/Erbb2/Neu (1-652)-Flag tag (DDDDK) fusion protein

HER36-R-50 50 ug
EUR 1207

These findings indicate a shifting epidemiology of arboviral disease in West Africa and highlight a need for increased research and implementation of vector and disease control. Rapid urbanization and climate change may further alter disease patterns, underscoring the need for improved diagnostic capacity, and vector and disease surveillance to address this evolving health challenge.