Perspectives on challenges and opportunities for birth defects surveillance programs during and after the COVID-19 era.

In recent months, various public health measures have been implemented throughout the world in response to the coronavirus disease 2019 (COVID-19) pandemic. This outbreak, and the subsequent containment policies, may have a range of potential short- and long-term impacts on the monitoring and surveillance of other conditions, such as birth defects. In this commentary, we provide a perspective on these potential impacts on birth defects surveillance and analysis.

We discuss possible effects on clinical birth defect diagnoses, routine birth defects surveillance system activities, and epidemiologic considerations, as well as opportunities for mitigating the impact of COVID-19. Like many other sectors of public health and medicine, birth defects surveillance programs may be faced with organizational and methodological obstacles in the wake of a changing landscape.

VX-661
A2664-5.1 10 mM (in 1mL DMSO)
EUR 92
Description: F508del CFTR corrector

VX-661
A2664-50 50 mg
EUR 352
Description: F508del CFTR corrector

VX-661
B1268-25 each
EUR 652.8

VX-661
B1268-5 each
EUR 210

miRZip-661 anti-miR-661 microRNA construct
MZIP661-PA-1 Bacterial Streak
EUR 620

Tezacaftor (VX-661)
510264 10.0mg
EUR 150

PKCB (Ab-661) Antibody
E11-8169B 100μg
EUR 225
Description: Available in various conjugation types.

PKCB (Ab-661) Antibody
8B8169 50ug
EUR 368
Description: PKCB (Ab-661) Antibody

hsa-miR-661 Primers
MPH01964 150 ul / 10 uM
EUR 145.2

EDA-ATPγS-DYQ-661
NU-1609-661Q 50µl
EUR 2548.1

EDA-GTPγS-DYQ-661
NU-1610-661Q 50µl
EUR 2548.1

EDA-ADP-DYQ-661
NU-802-661Q 40µl
EUR 1150.7

Aminoallyl-dUTP-DYQ-661
NU-803-661Q 40µl
EUR 1150.7

EDA-ATP-DYQ-661
NU-808-661Q 40µl
EUR 1150.7

EDA-GTP-DYQ-661
NU-820-661Q 40µl
EUR 1150.7

Aminoallyl-UTP-DYQ-661
NU-821-661Q 40µl
EUR 1150.7

EDA-m7GTP-DYQ-661
NU-824-661Q 40µl
EUR 1150.7

EDA-m7GDP-DYQ-661
NU-827-661Q 40µl
EUR 1150.7

p24-HIV(p24/661) Antibody
BNCH0661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCH0661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC700661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC700661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC810661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC810661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC800661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC800661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC550661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC550661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC430661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC430661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC610661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNC610661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCA0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), APC conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCAP0661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCAP0661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCP0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), PerCP conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody
BNCR0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), RPE conjugate, Concentration: 0.1mg/mL

hsa-miR-661 miRNA Antagomir
MNH03370 2 x 5.0 nmol
EUR 394.8

hsa-miR-661 miRNA Inhibitor
MIH03370 2 x 5.0 nmol
EUR 211.2

5-Propargylamino-ddUTP-DYQ-661
NU-1619-661Q 80µl
EUR 1150.7

5-Propargylamino-CTP-DYQ-661
NU-831-661Q 40µl
EUR 1150.7

5-Propargylamino-ddCTP-DYQ-661
NU-850-661Q 80µl
EUR 1150.7

5-Propargylamino-dCTP-DYQ-661
NU-809-661Q 80µl
EUR 1150.7

p24-HIV(p24/661), 1mg/mL
BNUM0661-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

hsa-miR-661 miRNA Agomir/Antagomir
AM2356 2 OD, 4 OD, 50 OD (size by request, 1 OD corresponds to 33 ug) Ask for price
Description: MicroRNA: hsa-miR-661Accession Number: MIMAT0003324Mature Sequence: UGCCUGGGUCUCUGGCCUGCGCGUhsa-miR-661 are small non-coding RNAs of 20-22 nucleotides, typically excised from 60-110 nucleotide foldback RNA precursor structures. miRNAs are involved in crucial biological processes, including development, differentiation, apoptosis, and proliferation, through imperfect pairing with target messenger RNAs (mRNAs) of protein-coding genes and the transcriptional or post-transcriptional regulation of their expression. Click here to browse detailed information about hsa-miR-661 in miRBase.What is MicroRNA Agomir/Antagomir?MicroRNA Agomir is a special-labeled and chemically modified double-stranded small RNA that mimics the endogenous miRNA to regulate the biological function of the target gene. MicroRNA Antagomir is an especially chemically modified miRNA antagonist. It strongly competes with mature miRNAs in the body to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.Why choose hsa-miR-661 miRNA Agomir/Antagomir from Gentaur has extended experience in MicroRNA Agomir/Antagomir synthesis services that cover all human, mouse, and rat miRNAs in the current miRBase. Compared to standard miRNA mimics and inhibitors, Gentaur miRNA agomir and antagomir are more resistant to degradation, thus having a lasting effect: minimum for 1 week, up to 5-6 weeks. These products can be used in in vitro or in vivo miRNA functional studies.

p24-HIV(p24/661), 0.2mg/mL
BNUB0661-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), 0.2mg/mL
BNUB0661-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

γ-(6-Aminohexyl)-ATP-DYQ-661
NU-833-661Q 80µl
EUR 1150.7

γ-(6-Aminohexyl)-GTP-DYQ-661
NU-834-661Q 80µl
EUR 1150.7

N6-(6-Aminohexyl)-dATP-DYQ-661
NU-835-661Q 40µl
EUR 1150.7

N6-(6-Aminohexyl)-ATP-DYQ-661
NU-805-661Q 80µl
EUR 1150.7

EDA-AppNHp (EDA-AMPPNP)-DYQ-661
NU-810-661Q 40µl
EUR 1150.7

MAP Kinase Substrate; EGF-R (661-681)
5-01501 4 x 1mg Ask for price

Polyclonal MYOM2 / Myomesin 2 Antibody (aa612-661)
APR03243G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MYOM2 / Myomesin 2 (aa612-661). This antibody is tested and proven to work in the following applications:

7-Propargylamino-7-deaza-dATP-DYQ-661
NU-1611-661Q 40µl
EUR 1150.7

7-Propargylamino-7-deaza-ddATP-DYQ-661
NU-1612-661Q 80µl
EUR 1150.7

7-Propargylamino-7-deaza-dGTP-DYQ-661
NU-1615-661Q 40µl
EUR 1612

7-Propargylamino-7-deaza-ddGTP-DYQ-661
NU-1618-661Q 80µl
EUR 1733.4

8-(6-Aminohexyl)-amino-cGMP-DYQ-661
NU-832-661Q 80µl
EUR 1150.7

8-(6-Aminohexyl)-amino-cAMP-DYQ-661
NU-851-661Q 40µl
EUR 1150.7

8-(6-Aminohexyl)-amino-ATP-DYQ-661
NU-807-661Q 80µl
EUR 1150.7

8-(6-Aminohexyl)-amino-GMP-DYQ-661
NU-829-661Q 80µl
EUR 1150.7

8-(6-Aminohexyl)-amino-GTP-DYQ-661
NU-830-661Q 80µl
EUR 1150.7

STN 661-297*105-B7541 AC Signs
251421 Card of 1 Pictogram(s)
EUR 6.5
Description: Description Dutch: Gebodspictogram - Veiligheidsbril verplicht - Veiligheidsbril verplicht; Description French: Pictogramme d'obligation - Veiligheidsbril verplicht

STN 661-450*150-B7527 AC Signs
253221 Card of 1 Pictogram(s)
EUR 15.95
Description: Description Dutch: Gebodspictogram - Veiligheidsbril verplicht - Veiligheidsbril verplicht; Description French: Pictogramme d'obligation - Veiligheidsbril verplicht

STF 661-297*210-B7541 AC Signs
223297 Card of 1 Pictogram(s)
EUR 8.6
Description: Description Dutch: Gecombineerde Pictogrammen - Haute tension Danger de mort Accès interdit à toute personne étrangère au service; Description French: Pictogramme - Haute tension Danger de mort Accès interdit à toute personne étrangère au service

STF 661-450*300-B7527 AC Signs
223298 Card of 1 Pictogram(s)
EUR 18.78
Description: Description Dutch: Gecombineerde Pictogrammen - Haute tension Danger de mort Accès interdit à toute personne étrangère au service; Description French: Pictogramme - Haute tension Danger de mort Accès interdit à toute personne étrangère au service

p24-HIV(p24/661), CF594 conjugate, 0.1mg/mL
BNC940661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF594 conjugate, 0.1mg/mL
BNC940661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF488A conjugate, 0.1mg/mL
BNC880661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF488A conjugate, 0.1mg/mL
BNC880661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF647 conjugate, 0.1mg/mL
BNC470661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF647 conjugate, 0.1mg/mL
BNC470661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF568 conjugate, 0.1mg/mL
BNC680661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF568 conjugate, 0.1mg/mL
BNC680661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF405M conjugate, 0.1mg/mL
BNC050661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF405M conjugate, 0.1mg/mL
BNC050661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF405S conjugate, 0.1mg/mL
BNC040661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF405S conjugate, 0.1mg/mL
BNC040661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF640R conjugate, 0.1mg/mL
BNC400661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), CF640R conjugate, 0.1mg/mL
BNC400661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), Biotin conjugate, 0.1mg/mL
BNCB0661-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

p24-HIV(p24/661), Biotin conjugate, 0.1mg/mL
BNCB0661-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

FOXO3 (661-673) goat polyclonal antibody, Aff - Purified
AP23030PU-N 50 µg Ask for price

Olfr661 (untagged) - Mouse olfactory receptor 661 (Olfr661), (10ug)
MC213894 10 µg Ask for price

Human pre-microRNA Expression Construct Lenti-miR-661
PMIRH661PA-1 Bacterial Streak
EUR 620

Recombinant Brucella Abortus bhuA Protein (aa 1-661)
VAng-Lsx5157-inquire inquire Ask for price
Description: Brucella Abortus biovar 1 (strain 9-941) Heme transporter BhuA, recombinant protein.

Recombinant Brucella Suis bhuA Protein (aa 1-661)
VAng-Lsx5721-inquire inquire Ask for price
Description: Brucella Suis biovar 1 (strain 1330) Heme transporter BhuA, recombinant protein.

Recombinant Treponema Pallidum tkt Protein (aa 1-661)
VAng-Cr0963-inquire inquire Ask for price
Description: Treponema Pallidum (strain Nichols) transketolase (tkt), recombinant protein.

Recombinant Clostridium Difficile fbp Protein (aa 1-661)
VAng-Lsx9156-inquire inquire Ask for price
Description: Clostridium Difficile (strain 630) Fructose-1,6-bisphosphatase class 3, recombinant protein.

Recombinant Pichia pastoris SNX4 Protein (aa 1-661)
VAng-Cr6678-inquire inquire Ask for price
Description: Pichia pastoris Sorting nexin-4 (SNX4), recombinant protein.

Recombinant Clostridium Tetani uvrB Protein (aa 1-661)
VAng-Lsx01835-inquire inquire Ask for price
Description: Clostridium Tetani UvrABC system protein B, recombinant protein.

Recombinant Mycobacterium Tuberculosis Rv0102 Protein (aa 1-661)
VAng-Yyj0176-1mgEcoli 1 mg (E. coli)
EUR 8077.2
Description: Mycobacterium Tuberculosis Uncharacterized protein Rv0102/MT0111 (Rv0102, MT0111), recombinant protein.

Zfp661 (GFP-tagged) - Mouse zinc finger protein 661 (Zfp661)
MG206801 10 µg Ask for price

Olfr661 (GFP-tagged) - Mouse olfactory receptor 661 (Olfr661), (10ug)
MG215308 10 µg Ask for price

Olfr661 (Myc-DDK-tagged) - Mouse olfactory receptor 661 (Olfr661)
MR215308 10 µg Ask for price

Recombinant Caenorhabditis Elegans lst-2 Protein (aa 1-661)
VAng-Ly3528-inquire inquire Ask for price
Description: Caenorhabditis Elegans lateral signaling target protein 2 (lst-2), partial, recombination protein.

Recombinant Trypanosoma Brucei HSP70-4 Protein (aa 1-661)
VAng-Wyb8104-inquire inquire Ask for price
Description: Trypanosoma Brucei brucei Heat shock 70 kDa protein 4, partial, recombinant protein.

Recombinant HCV-1c E2 Protein (aa 384-661) [His]
VAng-Wyb7362-100g 100 µg
EUR 2096.4
Description: Hepatitis C virus (serotype 1c,isolate HC-G9) E2 protein, recombinant protein.

Recombinant HCV-1c E2 Protein (aa 384-661) [His]
VAng-Wyb7362-20g 20 µg
EUR 814.8
Description: Hepatitis C virus (serotype 1c,isolate HC-G9) E2 protein, recombinant protein.

Recombinant HCV-1c E2 Protein (aa 384-661) [His]
VAng-Wyb7362-50g 50 µg
EUR 1455.6
Description: Hepatitis C virus (serotype 1c,isolate HC-G9) E2 protein, recombinant protein.

HIV type 1 Glycoprotein 140 (aa 37 - 661)(Du151) [His]
DAG2131 100 µg Ask for price

8-(6-Aminohexyl)-amino-adenosine-3',5'-bisphosphate-DYQ-661
NU-811-661Q 40µl
EUR 1150.7

8-(6-Aminohexyl)-amino-adenosine-2',5'-bisphosphate-DYQ-661
NU-812-661Q 40µl
EUR 1150.7

Olr661 (untagged ORF) - Rat olfactory receptor 661 (Olr661), (10 ug)
RN214482 10 µg Ask for price

Recombinant Brucella Abortus bhuA Protein (strain 2308) (aa 1-661)
VAng-Lsx4953-inquire inquire Ask for price
Description: Brucella Abortus (strain 2308) Heme transporter BhuA, recombinant protein.

Alkaline Phosphatase (ALPL) mouse monoclonal antibody, clone BGN/03/661, Purified
BM216 200 µg Ask for price

Zfp661 (untagged) - Mouse zinc finger protein 661 (Zfp661), transcript variant 1, (10ug)
MC204724 10 µg Ask for price

Olr661 (Myc-DDK-tagged ORF) - Rat olfactory receptor 661 (Olr661), (10 ug)
RR214482 10 µg Ask for price

Lenti ORF clone of Olfr661 (mGFP-tagged) - Mouse olfactory receptor 661 (Olfr661)
MR215308L4 10 µg Ask for price

A better understanding of these potential challenges faced by birth defects surveillance programs could facilitate better planning and collaboration across programs to overcome barriers to core activities and to prepare for novel opportunities for research and prevention.